Dimethyl sulfoxide (DMSO) is one of the most studied pharmaceutical agents of our time. Over 40,000 articles on its chemistry have appeared in scientific journals along with thousands of laboratory studies. DMSO works for a variety of ailments, including pain relief, inflammation reduction, scleroderma, interstitial cystitis, and arthritis treatment and even elevated intercranial pressure. DMSO has the ability to pass through membranes very quickly and will transport other things with it for deep tissue penetration. DMSO is most widely as a topical analgesic that works by blocking peripheral nerve C fibers and relief is reported to be almost immediate, lasting up to 6 hours.